by Peptide synthesis involves the chemical production of peptides, which are short chains of amino acids linked by peptide (amide) bonds. Peptides play a crucial role across various biomedical and pharmaceutical sectors, owing to their ability to replicate the physiological activity of naturally occurring peptides and proteins.
The global peptide synthesis market is estimated to be valued at US$ 490.58 mn in 2024 and is expected to exhibit a CAGR of 7.4% over the forecast period 2024 to 2031.
Peptides are used extensively in drug discovery and development processes as alternatives to traditional small molecule drugs. They can modulate biological processes by binding to G protein-coupled receptors and ion channels. Advantages such as high specificity, low toxicity, and minimal immunogenicity have increased the adoption of peptides in therapeutic areas such as oncology, metabolic diseases, CVD, and immunology. The global Peptide Synthesis Market Trends is driven by growing R&D investments in biopharmaceutical and biotechnology sectors. Additionally, increasing demand for personalized medicines and recent technological advancements in peptide synthesis methods are expected to propel market growth.
Key Takeaways
Key players operating in the peptide synthesis market include GenScript Biotech Corporation, Merck KGaA, ThermoFisher Scientific Inc., Syngene, Lonza, Novo Nordisk A/S, Bachem Holding AG, Gyros Protein Technologies, Creative Diagnostics, CEM Corporation, PuroSynth. The demand for peptide synthesis in drug discovery and development is increasing rapidly due to rising focus on developing novel therapeutics. Additionally, increasing prevalence of various chronic and lifestyle-related diseases is augmenting the need for novel peptides and proteins. Technological advancements in the field of automated peptide synthesizers, recombinant peptide production, and analytical techniques are further aiding market growth.
Market Trends
Increase in Outsourcing of Peptide Synthesis: Major pharmaceutical and biotech companies are outsourcing peptide production to specialized vendors due to lack of in-house production capabilities. This is expected to drive the market during the forecast period.
Rise of Solid-Phase Peptide Synthesis: Traditional solution phase peptide synthesis methods are gradually being replaced by more advanced solid-phase peptide synthesis techniques that enable rapid, cost-effective, and high-yield production of peptides.
Market Opportunities
Development of Therapies for Rare and Orphan Diseases: Peptide Synthesis Market Size And Trends offer promising opportunities for treating rare diseases with high unmet needs. Increasing availability of funding to develop orphan drugs will create more prospects.
Growth Opportunities in Emerging Markets: Establishing cost-effective production facilities, along with marketing and distribution channels in fast-growing pharma markets such as Asia Pacific, Middle East, and Latin America can present lucrative opportunities.
Impact of COVID-19 on Peptide Synthesis Market Growth
The COVID-19 pandemic has profoundly impacted the growth of the global peptide synthesis market. Lockdowns and movement restrictions imposed to curb the spread of the virus disrupted the global supply chains of raw materials required for peptide synthesis. This led to uncertainties in the availability and prices of critical materials like amino acids. It also impacted scheduled deliveries, resulting in delayed research projects. The shutdown of research laboratories and facilities reduced the demand for custom peptides from academic and pharmaceutical institutions.
However, with the urgent need for developing diagnostic tools and vaccines against coronavirus, investments in peptide-based research surged post lockdowns. Various studies evaluating T-cell responses and developing epitope-based vaccines relied on custom peptides. This resurgence in peptide-based research projects supported the recovery of market demand. Manufacturers also adopted strategies like maintaining buffer stocks and diversifying raw material sourcing to improve supply chain resilience. While short term obstacles were faced, COVID-19 has highlighted the importance of continued investments in life science research and healthcare preparedness, factors which are likely to drive long term growth in the peptide synthesis market.
Geographical Regions with High Peptide Synthesis Market Value
North America accounts for the largest share of the global peptide synthesis market in terms of value. This is attributed to sizable investments in biotechnology and pharmaceutical R&D by both private organizations and government agencies in the US and Canada. Europe holds the second largest market share due to strong presence of contract research organizations and custom peptide manufacturers in countries like Germany, UK and France serving the pharmaceutical and diagnostic sectors. Asia Pacific is the fastest growing regional market for peptide synthesis driven by expanding biomanufacturing capabilities and increasing focus on native healthcare solutions in major economies like China and India.
Fastest Growing Region for Peptide Synthesis Market
Asia Pacific is poised to be the fastest growing regional market for peptide synthesis during the forecast period. This growth can be attributed to rising investments by China and India in developing their domestic biotechnology industries. Both countries offer strategic advantages for investment like large talent pools, lower production costs and a growing local market demand for healthcare and biologics. Government initiatives in these nations are providing impetus for setting up manufacturing facilities and R&D centers. This is attracting global peptide synthesis companies to expand into Asia to leverage new opportunities. Additionally, Asia Pacific has a high disease burden that is driving indigenous research on novel therapeutics derived from custom peptides. All these factors are fueling the rapid rise of the peptide synthesis market across Asia Pacific.
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1.Source: Coherent Market Insights, Public sources, Desk research
2.We have leveraged AI tools to mine information and compile it
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