May 18, 2024
Brain Signals

Brain Signals Initiate Rapid Liver Adaptations to Food: A Game Changer in Type 2 Diabetes Research

New research from the Max Planck Institute for Metabolism Research reveals that the liver’s metabolic responses to food are initiated in the brain within a matter of minutes. The team discovered this intriguing process by observing mice that were exposed to food but not allowed to eat it.

The sight and smell of food triggered a group of nerve cells in the brain, which in turn sent signals to the liver. These signals prompted the liver mitochondria to undergo changes, preparing the liver for the upcoming sugar metabolism adjustments. The team’s findings, published in the journal Science, could pave the way for innovative treatments for type 2 diabetes.

The researchers conducted experiments on hungry mice that were presented with food but prevented from consuming it. After a brief exposure, the scientists analyzed the liver mitochondria and found that several processes typically initiated by food intake had already been activated.

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