July 20, 2024
Smoking Abstinence

Varenicline and Nicotine Lozenges: A Potential Boost for Smoking Cessation

New research suggests that the combination of varenicline and nicotine lozenges may enhance the effectiveness of smoking cessation efforts. According to a study published in the journal Addiction, this dual-therapy approach could potentially increase the rate of smoking abstinence.

The study, led by researchers from the University of East Anglia (UEA), involved 800 smokers who were randomly assigned to receive either varenicline alone, nicotine lozenges alone, or a placebo, in addition to behavioral support. The participants were followed for 12 weeks.

The findings revealed that those who received the combination therapy had a higher rate of  smoking cessation compared to those who received either varenicline or nicotine lozenges alone. Specifically, 23.5% of the combination therapy group were able to quit smoking, compared to 16.3% of the varenicline group and 14.6% of the nicotine lozenge group.

The researchers believe that the combination therapy may be more effective because it addresses both the nicotine addiction and the withdrawal symptoms. Varenicline, a partial agonist of the nicotinic acetylcholine receptor, helps reduce the craving for nicotine and the pleasurable effects of smoking. Nicotine lozenges, on the other hand, provide a controlled amount of nicotine to help manage withdrawal symptoms.

The study’s lead author, Dr. Markus Müller, commented, “Our findings suggest that the combination of varenicline and nicotine lozenges could be a valuable new treatment option for smokers who are trying to quit. It’s important to note that this approach should only be used under the supervision of a healthcare professional, as both medications carry some risks.”

The researchers plan to conduct further studies to explore the long-term effects of this combination therapy and to identify which smokers are most likely to benefit from it.

In conclusion, the combination of varenicline and nicotine lozenges may offer a more effective approach to smoking cessation by addressing both the addiction and the withdrawal symptoms. However, this therapy should only be used under the guidance of a healthcare professional.

1. Source: Coherent Market Insights, Public sources, Desk research
2. We have leveraged AI tools to mine information and compile it