by Plasmid DNA is circular DNA molecules that can replicate independently of the chromosomal DNA. They are employed as therapeutic agents in gene and cell therapies. Plasmid DNA is used as a raw material for several types of gene therapies such as cancer immunotherapy, vaccine development, and genetic disorder treatments. The demand for plasmid DNA is growing due to the increasing investment in cell and gene therapy research and development activities. Plasmid DNA manufacturing is a complex multi-step process that involves bacterial fermentation, downstream processing, quality checking, and formulation.
The global plasmid DNA manufacturing market is estimated to be valued at US$ 1038.19 Mn in 2024 and is expected to exhibit a CAGR of 4.8% over the forecast period 2024 to 2031.
Key Takeaways
Some of the key players operating in the plasmid DNA manufacturing market are Cobra Biologics and Pharmaceutical Services (Charles River Laboratories), VGXI, Inc., Aldevron (Danaher), Kaneka Corporation, Nature Technology, PlasmidFactory GmbH & Co. KG, Cell and Gene Therapy Catapult, LakePharma, Inc., MeiraGTx Limited, Eurofins Genomics, Vigene Biosciences, Luminous BioSciences (LBS), LLC, GenScript, GENEWIZ, Creative Biogene, Akron Biotech, Biomay, JAFRAL Ltd., WuXi Biologics, GeneImmune Biotechnology Corp., Lonza, Greenpak Biotech Ltd., Luina Bio (AcuraBio), Ajinomoto Bio-Pharma, Synbio Technologies, Genopis Inc., Altogen Biosystems, Puresyn, Inc., Cepham Life Sciences, Catalent, Inc., Biomiga, Waisman Biomanufacturing.
– Key players operating in the plasmid DNA manufacturing market are Cobra Biologics and Pharmaceutical Services (Charles River Laboratories), VGXI, Inc., Aldevron (Danaher), Kaneka Corporation, Nature Technology, PlasmidFactory GmbH & Co. KG among others.
– Increasing R&D investments in cell and gene therapy development present huge opportunities for plasmid DNA manufacturers. The growing clinical pipeline will augment the demand.
– Major players are expanding globally to cater to the increasing demand from biopharma companies and research institutes. Increased adoption in emerging markets like Asia will drive the market growth.
Market Drivers
Rapidly growing clinical pipeline of cell and gene therapies is a major factor driving the Plasmid DNA Manufacturing Market Demand Increased research activities will augment the demand.
– High unmet medical needs for diseases like cancer and genetic disorders are propelling the development of plasmid DNA based therapeutics. This presents an attractive opportunity for market players.
PEST Analysis
Political: There is growing support from governments worldwide for stem cell research and development of regenerative medicine therapies, which is positively impacting the market.
Economic: Rising healthcare expenditure globally and growing investment in biotechnology and life sciences research are fueling market growth.
Social: Increasing incidence of chronic diseases and demand for advanced treatment options are driving demand for Plasmid DNA Manufacturing Market products used in development of targeted therapies.
Technological: Sophisticated gene synthesis technologies, automation in manufacturing processes, and adoption of single-use systems are enhancing production efficiency and speeds.
Geographic Concentration
In terms of value, North America accounts for the largest share of the market currently due to major players being based in the US and high funding for life sciences research. Growth is also strong in Asia Pacific due to increasing investments by China and India into biotech infrastructure and genomics research.
Fastest Growing Region
Asia Pacific region is expected to grow at the fastest rate during the forecast period. This can be attributed to large population and rising healthcare needs in emerging economies like China and India. Initiatives to promote domestic biotech and biosimilar industries are also propelling the market in Asia Pacific forward.
*Note:
1. Source: Coherent Market Insights, Public sources, Desk research
2. We have leveraged AI tools to mine information and compile it.
Ravina Pandya, Content Writer, has a strong foothold in the market research industry. She specializes in writing well-researched articles from different industries, including food and beverages, information and technology, healthcare, chemical and materials, etc. With an MBA in E-commerce, she has an expertise in SEO-optimized content that resonates with industry professionals.
