February 24, 2024
Bioreactors Market

The Advancements in Cell Culture Technologies is Driving the Bioreactors Market

Bioreactors Market

Bioreactors are container systems which are used for large-scale cultivation of cells under controlled conditions. Bioreactors allow precise environment control and monitoring parameters like temperature, pH, oxygen level during cell cultivation. They find extensive use in research and commercial applications for production of monoclonal antibodies, enzymes, vaccines. Continuous developments in cell culture techniques have led to enhanced scale production capabilities to meet growing therapeutic demand.

Bioreactors play a key role in pharmaceutical manufacturing as they allow development of efficient and scalable processes for production of biological therapeutics from mammalian as well as microbial cells. Advancements like single-use and functionally closed technologies have simplified operations and reduced costs. Integration of sensors for real-time monitoring of critical process parameters further aids in ensuring product quality and yield. Bioreactors are also employed in production of cell-based therapies like chimeric antigen receptor T (CAR-T) cell therapies which involve isolation, activation and enrichment of patient’s T-cells outside the body before reintroducing them to fight cancer. Growing pipeline of cell and gene therapy products will thereby continue boosting demand for technologies facilitating their commercial scale manufacturing.

The global Bioreactors Market is estimated to be valued at US$ 20.5 Bn in 2023 and is expected to exhibit a CAGR of 11% over the forecast period 2023 to 2030, as highlighted in a new report published by Coherent Market Insights.

Market key trends
The key trend in the bioreactors market size is the increasing demand for single-use bioreactors. Single-use bioreactors offer advantages like low risk of cross-contamination, low hold-up volumes, and ease of cleaning validations. They are proving to be an economical alternative to conventional stainless-steel bioreactors. Manufacturers are also developing functionally closed bioreactor systems integrated with in-line sensors, pumps and disposable tubing sets which minimize manual interventions. This is particularly important for manufacturing therapies involving cell and gene therapies where risk of contamination needs to be mitigated.

Porter’s Analysis
Threat of new entrants: The high initial capital expenditure and stringent regulatory norms in the biopharmaceutical industry poses significant barriers to new entrants. However, advancements in technology is lowering the entry barriers.
Bargaining power of buyers: The bargaining power of buyers is moderate due to the presence of several biopharmaceutical companies offering similar products. However, innovations and specialized offerings provide some differentiation.
Bargaining power of suppliers: Majority of the components used in bioreactors are highly technical and proprietary in nature, increasing the bargaining power of suppliers. However, large portfolio players have capability to develop in-house components as well.
Threat of new substitutes: There exists limited threat from substitutes currently but continuous innovation may lead to development of substitutes with better efficiency and lower cost of production.
Competitive rivalry: The biopharmaceutical industry witnesses intense competition due to presence of major global as well as local players operating at international level. Price wars and new product launches are common.

Key Takeaways
The global bioreactors market is expected to witness high growth. The global Bioreactors Market is estimated to be valued at US$ 20.5 Bn in 2023 and is expected to exhibit a CAGR of 11% over the forecast period 2023 to 2030.

Regional analysis: North America dominated the global market and is expected to maintain its lead position during the forecast period driven by strong presence of major players and continuous technological advancements in bioprocessing. Asia Pacific is anticipated to register highest growth rate owing to expanding biopharmaceutical industry, rising investments in R&D and improving regulatory environment.

Key players: Key players operating in the bioreactors market are Pfizer, Inc., Novartis AG, Kite Pharma, Inc., Bluebird bio, Inc., and Boehringer Ingelheim International GmbH. Pfizer and Novartis account for major share due to their dominance across multiple therapeutic segments and strong distribution networks globally.

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  1. Source: Coherent Market Insights, Public sources, Desk research
  2. We have leveraged AI tools to mine information and compile it